Role of cefpodoxime in the treatment of ear infections

Background: Acute otitis media (AOM) is a community-acquired respiratory tract infection in childhood frequently encountered by primary-care physicians and can cause significant morbidity. Increasing bacterial resistance has led to concern about the current options for empirical antibiotic treatment prompted search effective treatments. Objectives: To evaluate clinical efficacy safety of cefpodoxime proxetil children with acute media. Patients methods: A prospective, multicenter study was conducted on 1380 aged from 1 13 years AOM who were prescribed 5–10 day course (8 mg/kg/day). followed-up after 7–14 days baseline visit. Efficacy assessed percentage patients cure, improvement or failure at follow-up Safety evaluated recording occurrence severity any adverse events physicians’ patients’ assessment overall tolerability. Results: Clinically, 82.5% cured, 16.4% improved there therapy 1.1% patients. The combined cure rate all related signs symptoms 98.9%. Adverse events, diarrhea skin rash, reported only 16 (1.2%).